- Sparkle Car Wash
- Sparkle Clean
- Sparkle Cleaners
- Sparkle Cleaning Service
- Sparkling Cleaners
- Sparks Computerized Car Care
- Sparks Medical Foundation
- Sparky's
- Sparky's Food Store
- Sparky's One Stop
- Spartan Stores
- Spartech Plastics
- SPCA
- Speakeasy
- Special Counsel
- Special Creations
- Special Events
- Special F-X
- Special Moments
- Special Olympics
- Special Tee's
- Special T'S
- Specialized Services
- Specialty Auto
- Specialty Auto Sales
- Specialty Automotive
- Specialty Environmental Services
- Specialty Products
- Specialty Retail Ventures
- Specialty Shop
- Specialty Welding
- Specialtys
- Specs in the City
- Spec's Wines Spirits & Finer Foods
- Spectacle Shop
- Spectacle Shoppe
- Spectra Contract Flooring
- Spectrum Apartment Search
- Spectrum Communications