- Spotless Cleaners
- Spotlight Video
- Spraying Systems
- Spring Cleaners
- Spring Creek Apartments
- Spring Garden
- Spring Hill Apartments
- Spring Lake Apartments
- Spring Valley Apartments
- Springhill Suites by Marriott
- Springs
- Springwood Apartments
- Sprint
- Sprint - Sprint Pcs- Business Sales Office
- Sprint - Sprint Pcs- PCS Wireless
- Sprint Food Stores
- Sprint Lube
- Sprint PCS Personal Communications Services
- Sprint Print
- Sprint Store Express
- Sprintnet
- Sprouts
- Spudnuts Donuts
- Square One
- Square Plus Operating Corporation
- Square Plus Operating Corporation - Stations
- Squeaky Clean
- Squeaky Clean Car Wash
- SRS
- St Andrews Apartments
- St Anthony of Padua
- St Croix Shop
- St David's Rehabilitation Services
- St Elizabeth Medical Center
- St Francis
- St Francis Animal Hospital
- St Francis Bank
- St Francis Convent
- St Francis Hospital